Agilent Automation Solutions Automatic productivity for life sciences discovery brochure
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1. Agilent Automation Solutions Automatic productivity for life science discovery Our measure is your success products applications software services ioe Agilent Technologies Agilent Automation Solutions If you want to increase your pace of discovery here s where to start Whether you re a biotech start up still doing everything on the bench or working with automation in a multinational pharmaceutical company Agilent Automation Solutions can help you accelerate your discovery Automatically Our proven Agilent reliable automation platforms are speeding up cycle times and maximizing productivity on every scale covering the full spectrum of life science discovery applications 7A i Applications for Life Science Discovery lt 7 _ A ha a e High throughput screening e Compound management and high speed plate replication e Genomics sample prep PCR sequencing RNA purification and analysis e ADME Tox assays e Cell maintenance and processing e Cell based screening Etsy 1 JO 23 ee 10 Fast flexible solutions let you address today s bottlenecks without adding any new ones From high performance benchtop workstations to large fully integrated systems Agilent combines creative automation approaches with personalized service and support Our goal is to increase your lab s efficiency and walk away time and our easily customizable application solutions2. and control your laboratory automation assets across your entire discovery pipeline See page 10 amp f Integrated systems i Application specific or multi workflow cii 1 F systems such as the BioCel system Ty H ehig NAI let you automate and accelerate cn game 3 everything from cell maintenance to microplate replication to multiplexed high content assays See page 9 Benchtop workstation solutions By combining our versatile Bravo Automated Liquid Handling Platform and a variety of modular components you can automate genomics workflows high throughput screening plate maintenance and more See page 8 To learn more about Agilent Automation Solutions visit www agilent com lifesciences automation Liquid Handling Solutions Unmatched precision Unbeatable versatility Agilent liquid handling instruments deliver superior precision as well as rock solid day after day reliability for results you can depend on every time Bravo Automated Liquid Handling Platform The fastest smallest most versatile liquid handling system available The Bravo Automated Liquid Handling Platform s nine plate position footprint easily fits inside a standard laminar flow hood enabling automated liquid handling for cell based assays or hazardous reagents The unit automatically performs multi channel pipetting and serial dilutions in 96 384 and 1536 well formats and can also dispense to a sin
3. footprint Low vibration Dampening isolates vibration from mounting surface and minimizes impact on adjacent instruments Microplate Barcode Labeler Label one or all four sides of a microplate The Agilent Microplate Barcode Labeler fits easily on a bench top and prints up to six flelds bar codes and human readable per label The system can print at speeds up to one label every 3 seconds and can also apply barcode labels to microplates Using the optional barcode reader it can verity barcodes and reapply if necessary and create data clones and log barcode activity I inal Multiple configurations A wide selection of fonts barcode formats and magnifications allows maximum flexibility The convenient software can access a variety of data sources including comma or tab delimited files and spreadsheets and can be integrated with an ODBC compliant LIMS Microplate Seal Piercer Accurately pierce sealed microplates The Agilent Microplate Seal Piercer complements the PlateLoc Thermal Microplate Sealer and is used for screening or other applications that don t require tip washing between microplates It pierces a wide variety of seals on 96 or 384 well microplates in a cycle time of only 4 seconds Piercing head Interchangeable 96 or 384 pin heads are available with a variety of pin plate designs guaranteeing a clean controlled puncture every time with a penetration depth of 3 mm The pierce head i
4. ditional modules and new third party devices and the software includes a built in database capable of managing most labware including standard microplates filter plates deep well microplates tip boxes and tube racks Papi n Far i E Tp i TTT Be ee OY iv Ae mm oer i ETF rae E r ES g Te i Pmr mmn E T An easy to use drag and drop scheduler supports multiple plate formats and labware multiple protocols and linear and parallel process flows Hit pick wizard saves time and resources Need a hand adapting your workflows to automation Our experienced automation specialists can get you up and running in a hurry And if you ve got a question we Il get you the answers you need Fast To make sure your Agilent automation solution does everything you expect and more Agilent Application Scientists are a vital part of every workstation and integrated system collaboration They ll work with you to make sure your proposed solution Is optimally configured to meet the true demands of your application not just on paper but every day in the lab The Application team is also responsible for defining and performing the application testing on the system Of course we also provide expert installation familiarization and advanced training to make sure you continue to get maximum performance and productivity from your Agilent automation solution Agilent cert
5. ed completely customizable processing for medium and high throughput screening applications The Agilent BioCel 1800 System is a robust high performance automated platform specifically designed for cell culturing and cell based screening Rigorous environmental control protects and preserves your valuable cell lines ae Fi if E f aa a Ey EN d i It s all in how you put it together Using application proven standardized modular components we can help you create flexible solutions that meet your particular needs with rapid lead times and no development hassles The versatile systems are available in three sizes with various enclosure options and environmental control features They let you automate and accelerate everything trom cell maintenance to microplate replication to multiplexed high content assays including e High throughput screening e Secondary screening and ADMET assays e Genomics DNA extraction PCR sample preparation e Cell based assays ELISAs FLIPRs FACS and stem cell assays e Microplate based cell maintenance e Compound management e Enzyme assays Reproducible Standardized fully automated procedures improve the quality and consistency of cell based assays and other complex discovery operations and minimize experimental variability that could produce erroneous results Efficient Save time by reducing tedious costly manual inter ventions and increase your grou
6. give you the flexibility to solve problems today without the long lead time expense and uncertainty of from scratch solutions Built around robust proven hardware and software Agilent automation solutions provide an order of magnitude increase in throughput over manual or semi automated methods Compact easily configurable modules let you create a system that s exactly right for your lab and Its applications The result You get a level of fit with your needs you d expect only in fully customized solutions plus the dependability affordability and quick integration of standardized components A complete lineup of flexible scalable automation solutions Liquid handling Our automated liquid handling solutions span virtually all discovery applications They incorporate advanced fluid delivery technologies to deliver precise reliable performance as well as legendary Agilent reliability See page 4 Microplate handling Agilent s microplate handlers sealers centrifuges and barcode labelers deliver outstanding performance as stand alone instruments in versatile combinations or integrated into benchtop workstations or sophisticated robotic systems See page 6 zia ee e kee kr Fa ri 7 5 pte om ee oe z i i i ide H j re H a 5 k _ ee ee eee es eee Easy to use Agilent VWorks Automation Control software lets you integrate
7. gle well Offering numerous plate pad accessories and quick change out of various dispensing heads the deck is easily customized to meet a wide range of applications including e General Liquid Handling e Serial Dilutions e PCR Preparation and Cleanup e Cell based Assays e Filtration Assays Bravo Automated Liquid Handling Platform includes a configurable deck interchangeable 96 and 384 channel pipette heads and an e Magnetic bead based separations integrated plate gripper all in a compact space saving package Precise Proven high accuracy pipette heads dispense from 100 nL to 200 uL in 96 384 and 1536 well microplates in either disposable or fixed tip applications Versatile Seven different easy change head types can be swapped in minutes and numerous plate pad options are available to enable a wide range of assays and liquid handling applications Easy to integrate Unique open design allows access from all sides for simple system integration as well as stand alone use LACE R Riad Vertical Pipetting Station has eight sliding shelves on either side of the pipetting head allowing easy access to microplates while conserving deck space Vertical Pipetting Station Industry leading speed and unparalleled performance Serving either as a stand alone unit or integrated into a larger robotic platform Agilent s Vertical Pipetting Station significantly reduces cycle times for your most demanding sa
8. ified automation consumables and accessories To make sure your applications continue to perform flawlessly Agilent Automation Solutions provides high quality veritied validated and application tested consumables such as pipette tips microplate seals and microplate barcode label stock We also supply a growing range of accessories that help you perform your applications with greater ease and speed To learn more about Agilent Automation Solutions visit www agilent com lifesciences automation 11 So when do we start The first step on a faster path to discovery starts with a phone call to your Agilent representative To find out more about our automation solutions for discovery and beyond call today For more information Learn more www agilent com lifesciences automation Buy online www agilent com chem store Find an Agilent customer center in your country www agilent com chem contactus U S and Canada 1 800 227 9770 agilent_inquiries agilent com Europe info_agilent agilent com Asia Pacific adinquiry_aplsca agilent com Research use only Information descriptions and specifications in this publication are subject to change without notice Agilent Technologies shall not be liable for errors contained herein or for incidental or consequential damages in connection with the furnishing performance or use of this material Agilent Technologies Inc 2009 Printed in USA August 4 2009 0990 4246EN
9. mple handling and liquid transfer applications The pipette head s 2 axis positioning provides access to all quadrants of 96 384 and 1536 well microplates and an intuitive user interface lets you easily create and run complex pipetting protocols for operations such as e General liquid handling e Plate replication and reformatting e PCR preparation and cleanup Ultra compact design Unique eight plate position design in a footprint of only three plate positions allows seamless integration into automation systems High throughput Simultaneously pipetting while processed plates are replaced boosts throughput and significantly reduces assay time Versatile Pipetting range of 100 nL to 200 uL accommo dates virtually any application requirement pipette heads are easily interchanged in less than 2 minutes To learn more about Agilent Automation Solutions visit www agilent com lifesciences automation Microplate Handling Solutions All the speed and functionality a busy lab can use Along with liquid handling microplate handling is at the heart of just about every discovery lab With a complete selection of readily integratable modules Agilent can help you automate virtually every plate handling operation PlateLoc Thermal Microplate Sealer Fast small easy to use and easy to integrate Agilent s PlateLoc Thermal Microplate Sealer is not only one of the smallest most dependable plate sealers on the market i
10. p s productivity by running 24 7 Flexible Unique hardware and software architecture allows seamless integration of devices and instruments and easily accommodates future expansion The BioCel 900 and 1200 robots are capable of reaching outside of the system frame to permit the integration of large devices and instruments on docking tables In addition multiple BioCel systems can be combined to handle complex applications Direct Drive Robot One person one touch teaching You can teach the Agilent Direct Drive Robot just about anything with the click of a button One person can quickly integrate instruments into the system minimizing setup personnel and time To learn more about Agilent Automation Solutions visit www agilent com lifesciences automation 10 What makes these things so smart The same thing that makes Agilent automation solutions so easy to use VWorks Automation Control software VWorks provides a comprehensive interface for all of your Agilent lab automation Having a single platform reduces training costs and maximizes productivity and allows complete confident control for all levels of operators The software links Agilent and third party devices such as liquid handlers plate readers and washers to provide a cohesive integrated lab automation environment a system that helps you achieve maximum throughput and optimal resource utilization A flexible expandable architecture readily accommodates ad
11. plate handling and storage the BenchCel Microplate Workstation delivers speed and precision you would expect to find only in much larger systems The small footprint unit easily integrates popular laboratory devices with other Agilent automation components and features a high speed robot that can access peripheral instruments as well as its own microplate stacks to enable operations such as e Labeling and sealing e Centrifugation e Plate replication e Mix and read screening assays TE e PCR sample prep Easily customizable design of the Agilent BenchCel Microplate Handler gives you the flexibility and scalability to meet the needs of the most diverse discovery applications High speed 8 second transfer time from stack to instrument rivals even much larger automation systems Flexible capacity 2 4 or 6 rack options accommodate a maximum of 360 standard microplates Higher capacity gives you 66 more walk away time than competitive systems Convenience System provides storage and handling of most microplates lidded plates tip boxes and tube racks Delidding function adds even more versatility removing and replacing microplate lids as necessary BioCel Systems The perfect environment for higher productivity Agilent BioCel Systems combine the Agilent Direct Drive Robot the industry s most advanced robot for plate handling with sophisticated VWorks Automation Control software to deliver fully integrat
12. s easily removed for cleaning and can be changed in seconds for reconfiguration between formats Plate accessibility The unit can be loaded by hand or by articulated arm robot A hardware interlock on the front door ensures operator safety To learn more about Agilent Automation Solutions visit www agilent com lifesciences automation Automated Workstations and Custom Systems Modular convenience and affordability tailored for your application Agilent Automation Solutions offers customized workstations and systems scaled to meet the complete range of application requirements in today s discovery laboratory Genomics Proteomics Workstations Based on the versatile BenchCel Microplate Handler and Bravo Automated Liquid Handling Platform a typical automated genomics solution in the example above an RNAI workstation might also include a Microplate Barcode Labeler and PlateLoc Thermal Microplate Sealer shown Agilent automation components can be combined with a variety of industry leading plate readers washers and incubators to give you a compact benchtop solution for screening enzymes proteins antibodies or cells Other configurations can be assembled for bulk dispensing plate reading PCR setup cleanup genomic assays cell maintenance and cell viability applications BenchCel Microplate Workstation Compact benchtop system with the performance of a full size automation platform Combining automated micro
13. t s also the most versatile The module automatically adjusts to accommodate a wide range of standard microplates and tube racks for applications such as e Compound Storage e Screening e PCR qPCR rtPCR e Sequencing High precision With sealing temperature control of 2 C and advanced seal slitting control seal integrity is always the same for every microplate perfect High throughput Fast cycle times with no required cool down periods enable rapid microplate sealing and an easy to access top loading seal roll support minimizes downtime when replenishing consumables Microplate Centrifuge Stable high speed centrifugation with 3 second loading times The Agilent Microplate Centrifuge is a very compact robot accessible unit that provides both vibration and noise control in a small low maintenance package With a three second loading time and robust spin control it s ideal for high or medium throughput applications such as e Filtration protocols for PCR purification e Cell harvesting for plasmid preps e Condensate spin down for post PCR processes e Removal of air bubbles in high density plates Universally accessible With the automated centrifuge loader and high throughput door design the Microplate Centrifuge can be integrated with most robotic systems Stackable design Multiple Microplate Centrifuge units can be stacked on each other increasing the system throughput without adding to the
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Agilent Automation Solutions Automatic productivity for life sciences discovery brochure